Genesight

Pharmacogenomics is the study of how an individual’s unique genetic makeup may affect their outcomes with medications. GeneSight pharmacogenomic laboratory tests examine certain genetic characteristics that you may have which may affect your outcomes with many prescribed medications. The results of the test, along with other important non-genetic factors and the clinical experience and knowledge of your healthcare provider, may help him/her select more appropriate medications for you. 

Available Tests: 

GeneSight Psychotropic A pharmacogenomic laboratory test which examines fourteen genes (ADRA2A, CES1A1, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, HLA-A*3101, HLA-B*1502, HTR2A, SLC6A4, UGT1A4, and UGT2B15) that may affect many commonly prescribed antidepressant, antipsychotic, anxiolytic, hypnotic, mood stabilizing, stimulant, and non-stimulant medications. The test also reports on the genetic results for COMT. The COMT genotype is provided for informational purposes only, since studies assessing COMT genotype and response to psychotropic medications have not shown that COMT is a reliable marker of medication outcomes. 

GeneSight MTHFR A pharmacogenomic laboratory test which examines one gene (MTHFR) that may affect folic acid metabolism. 

CYP2D6 Single Gene Report A pharmacogenetic laboratory test which examines one gene (CYP2D6) that may affect metabolism of psychotropic medications, including aripiprazole, brexpiprazole, clozapine, desipramine, fluvoxamine, iloperidone, nortriptyline, paroxetine, perphenazine, risperidone, thioridazine, venlafaxine, or vortioxetine.

 CYP2C19 Single Gene Report A pharmacogenetic laboratory test which examines one gene (CYP2C19) that may affect metabolism of psychotropic medications, including citalopram, escitalopram, or sertraline. 

HLA-B*1502 Single Gene Report A pharmacogenetic laboratory test which examines one gene (HLA-B*1502) that is associated with side effects with oxcarbazepine.

 Please Understand:

 • This test can only be ordered by an appropriately licensed healthcare provider.

 • You may wish to obtain genetic counseling prior to or after having this test performed.

 • The genetic variants of this test may indicate how quickly medications are metabolized in the body or how you may respond to a medication.

 • The test examines the most common genetic variants in the tested genes. However, some less common variants may not be detected by the test. 

• The results of the test become part of your medical record. Results may be available to individuals/organizations with legal access to your medical records and others specifically authorized by you or your representative to access your medical records.

 • Unless authorized by you or your representative, no tests other than GeneSight will be completed on your biological sample. Your sample will be destroyed at the end of the testing process or not more than 60 days after the sample collection date.

 For more information, visit our website: GeneSight.com